Omnipod 5 Automated Insulin Delivery System
TŠOANTŠISO:
BAKENG SA BATHO BA NANG LE INSULIN E HLOKA MOFUTA OA 1 LEFU LA SEKERE LA LILEMO TSE 2 LE HO PHAHAMA.
Taolo ea Insulin e ikemetseng
taolo ea insulin e ikemetseng bakeng sa batho ba nang le lefu la tsoekere la mofuta oa 1
Omnipod 5* e nang le theknoloji ea SmartAdjust™ e laola phano ea insulin ka mafolo-folo metsotso e meng le e meng e 5 e sebelisa sepheo sa tsoekere e ikhethileng ho thusa ho fokotsa nako ea hyperglycemia le hypoglycaemia.b,c,d1
- Khetho ea litekanyetso tsa glucose ka nako ea letsatsi, ho pholletsa le letsatsi; e ka fetoha ho tloha ho 110–150 mg/dL (6.1–8.3 mmol/L)
- Ke eona feela Sistimi ea AID e nang le sebali sa SmartBolus, se tsebisitsoeng ka boleng le mokhoa oa Dexcom G6 CGM
OMNIPOD 5 TAOLO E Ntlafetseng ea GLYCEMIC BAKENG SA BAHOLO, BACHA, LE BANA BA T1D LITHUTO TSA BOHLOKOA C, D, F1, 2
- 76% ea nako e behiloeng ho 110mg/dl (6.1mmol/L) ho batho ba baholo le bacha (lilemo tse 14-70) le 68% ka kakaretso TIR ho bana (lilemo tse 2-13.9)
- HbA1c e fokotsehile haholo ho bana ba banyenyane haholo (lilemo tse 2.0-5.9), bana (lilemo tse 6-13.9), le batho ba baholo le bacha (lilemo tse 14-70) ka 0.5%, 0.7% le 0.4% ka ho latellana1,2
- 33% e fokolitse nako ea hyperglycemia ho bana, 24% ho batho ba baholo le bacha.
- Phokotso ea 60% ea hypoglycemia ka bosiu bo le bong le 46% ka kakaretso ho batho ba baholo le bacha 1
Liphetoho tseleng c,b1
Ha ho sa na liente tse ngata tsa letsatsi le letsatsi, li-tubing, kapa fingersticksh1
- E senang tube, e sa keneleng metsi, i Pod e nang le theknoloji e hahelletsoeng ka hare ho SmartAdjust™
- E kopantsoe le Sisteme e nepahetseng ea Dexcom G6 CGM j
HO OMNIPOD 5 THUTO EA BOHLOKOA
Batho ba baholo ba tlalehile khatello ea maikutlo e tlase ha ba ja ha ba bapisoa le kalafo ea pele c, g
Batsoali ba bana ba tlalehile boleng ba boroko bo betere ha bo bapisoa le phekolo ea pele c, g
Basebelisi ba baholo le batsoali ba bana ba ne ba ikutloa ba le sebete ho lula ba bolokehile kotsing ea hypoglycemia ha ba bapisoa le kalafo ea pele c,
Generation AID, CE e tšoailoe mme e tla haufinyane
Omnipod 5*–moloko o tlang oa AID, o tšoailoe ke CE 'me oa tla haufinyane
- Taolo e ntlafetseng ea glycemic ho lihlopha tsohle tsa lilemo ho tloha lilemong tsa 2 lithutong tse peli tsa bohlokoa, ha nako ea hypoglycemia e ntse e le tlaase b,c,d,f 1,2.
- Ha ho sa na liente tse ngata tsa letsatsi le letsatsi, li-tubing, kapa lithupa tsa menoana h1
- E senang tube, e sa keneleng metsi, iPod e nang le theknoloji e hahelletsoeng ka har'a SmartAdjust™
BUA REP LE HAO
SHEBA MELEMO EA OMNIPOD 5
Hore na e loketse ho feta CSII, kapa e hloka sistimi e bonolo ea ho fana ka insulin e se nang tube pele ho Omnipod 5… Omnipod DASH® e ka ba tharollo e ntle kajeno.
Boitsebiso ba Bohlokoa ba Tšireletseho
Omnipod 5 Automated Insulin Delivery System e reretsoe ho sebelisoa ke batho ba nang le lefu la tsoekere la Mofuta oa 1 ho batho ba lilemo tse 2 ho ea holimo. Omnipod 5 System e etselitsoe mokuli a le mong, tšebeliso ea lapeng 'me e hloka tlhokomelo ea mofani oa tlhokomelo ea bophelo ea mosebedisi. Omnipod 5 System e tsamaisana le li-insulin tse latelang tsa U-100: NovoLog®, Humalog® le Admelog®. Sheba ho Omnipod® 5 Automated Insulin Delivery System Guide le www.omnipod.com/safety bakeng sa tlhaiso-leseling e felletseng ea polokeho ho kenyelletsa matšoao, li-contraindication, litemoso, litemoso le litaelo.
Ha e sebelisoa ka mokhoa oa othomathike le Dexcom G6 CGM, Omnipod 5 System e etsa liphetoho ho phano ea insulin metsotsong e meng le e meng e 5 ho latela boleng ba CGM ba mosebelisi, boleng ba tsoekere bo boletsoeng esale pele metsotso e 60 nakong e tlang, mokhoa oa tsoekere le phepelo ea insulin e fetileng ho tlisa tsoekere. sepheo se hlalosoang ke mosebedisi. b E Hloka Dexcom G6 CGM. c Teko e lebelletsoeng ea bohlokoa ho barupeluoa ba 240 ba nang le T1D ea lilemo tse 6-70 (bacha ba 128 / batho ba baholo ba lilemo tse 14-70 le bana ba 112 ba lilemo tse 6¬–13.9). Thuto e kenyelelitse karolo ea 14 ea matsatsi a ST e lateloang ke khoeli ea 3 ea Omnipod 5 HCL phase. Tekanyo ea liketsahalo tsa hypoglycemia e matla le ketoacidosis ea lefu la tsoekere nakong ea AID e ne e le liketsahalo tsa 4.8 le 1.2 ka lilemo tse 100 tsa motho, ka ho latellana.1 d Khabareng (70-180 mg / dL [3.9-10.0 mmol / L]) joalokaha e lekantsoe ke CGM ho batho ba baholo / bacha le bana ST vs 3-khoeli Omnipod 5: 64.7% vs 73.9%, P<0.0001; 52.5% vs 68.0%, P<0.0001, ka ho latellana. Ho bolela HbA1c: tšebeliso ea motheo vs Omnipod 5 ho batho ba baholo / bacha le bana, ka ho latellana (7.16% vs 6.78%, P<0.0001; 7.67% vs 6.99%, P<0.0001).
Ho sa le joalo ka holimo ho marang-rang (> 180 mg / dL [10.0 mmol / L]) joalokaha e lekantsoe ke CGM ho batho ba baholo / bacha le bana ST vs 3-khoeli ea Omnipod 5: 32.4% vs 24.7%; 45.3% vs. 30.2%, P <0.0001, ka ho latellana. Nako e bohareng e ka tlaase ho moeli (<70 mg/dL [3.9 mmol/L]) joalokaha e lekantsoe ke CGM ho batho ba baholo/bacha le bana ST vs 3-khoeli ea Omnipod 5: 2.0% vs 1.1%, P<0.0001; 1.4% vs 1.5%, P=0.8153, ka ho latellana. Nako e mahareng e ka tlase ho moeli (<70 mg/dL [3.9 mmol/L]; 12 AM – <6 AM) joalo ka ha e lekantsoe ke CGM ho batho ba baholo/bacha le bana ST vs 3-khoeli Omnipod 5: 2.07% vs 0.82%, p< 0.0001; 0.78% vs 0.78%, P=0.0456, ka ho latellana. Lipapiso ke liphetoho tse lekanyelitsoeng.1 Lipheo tsa Glucose li ka fetoloa ho fihla ho likarolo tse 8 ka letsatsi. f Teko e lebelletsoeng ho barupeluoa ba 80 ba nang le T1D ba lilemo li 2–5.9. Thuto e kenyelelitse karolo ea 14 ea matsatsi a ST e lateloang ke khoeli ea 3 ea Omnipod 5 HCL phase.
Ho sa le joalo ka mefuta e fapaneng (70-180 mg / dL [3.9-10.0 mmol / L]) ho bana ba banyenyane haholo joalokaha e lekantsoe ke CGM: ST = 57.2%, likhoeli tse 3 Omnipod 5 = 68.1%, P<0.05. Ho bolela HbA1c: ST vs Omnipod 5 e sebelisoa ho bana ba banyenyane haholo 7.4% vs 6.9%, P<0.05. Nako e mahareng e ka tlase ho tekanyo (<70 mg/dL [3.9 mmol/L]) joalo ka ha e lekantsoe ke CGM: ST vs Omnipod 5 e sebelisoa ho bana ba banyenyane haholo (2.2% vs 1.9%, P<0.05).2 g Phekolo ea pele ho batho ba baholo le bana, ka ho latellana: 15.6% MDI, 84.4% CSII; 9.6% MDI, 90.4% CSII. Nakong ea teko ea bohlokoa ea Omnipod 5, batho ba baholo ba lilemo li 18-70 (N = 111) ba bile le ntlafatso ea lintlha tsa tlhahlobo ea khatello ea maikutlo ka mor'a likhoeli tsa 3 tsa tšebeliso ea Omnipod 5 ha ba bapisoa le ST: ho bolela T1-DDS Eating Distress Subscale: 1.74 vs. 1.97, ka ho latellana.
Batsoali ba bana ba lilemo tse 6-11.9 (N=82) le batho ba baholo ba lilemo li 18-70 (N=111) ba bile le ntlafatso ea lintlha tsa tlhahlobo ea kholiseho ea hypoglycemia ka mor'a likhoeli tse 3 tsa tšebeliso ea Omnipod 5 ha e bapisoa le ST: lintlha tsa HCS = 3.59 vs. 3.34; le 3.65 vs 3.52, ka ho latellana. Batsoali ba bana ba lilemo tse 6-11.9 (N = 82) ba bile le ntlafatso ea lintlha tsa tlhahlobo ea boleng ba boroko ka mor'a likhoeli tse 3 tsa tšebeliso ea Omnipod 5 ha ba bapisoa le ST: ho bolela PSQI Overall Sleep Quality Subscore = 0.70 vs 1.13, ka ho latellana.1 h Haeba litlhokomeliso tsa tsoekere le ho bala ho tsoa ho Dexcom G6 ha ho tsamaellane le matšoao kapa litebello, meter ea tsoekere ea mali e lokela ho sebelisoa ho etsa liqeto tsa kalafo ea lefu la tsoekere. i The Pod e na le boemo ba IP28 ho fihla ho maoto a 25 metsotso e 60. Selaoli ha se kenelle metsi. Sensor le transmitter ea Dexcom G6 ha li na metsi 'me li ka qoelisoa ka tlase ho maoto a robeli a metsi ho fihlela lihora tse 24 ntle le ho hloleha ha li kentsoe hantle. j Dexcom G6 CGM System e rekisoa ka thoko. Omnipod 5 System e tlameha ho sebelisoa le sesebelisoa sa Dexcom G6 mme ha e tsamaisane le moamoheli oa Dexcom G6.
AID, ho fana ka insulin ka boiketsetso; CGM, ho hlahloba tsoekere e tsoelang pele; CSII, infusion ea insulin e sa khaotseng; DKA, lefu la tsoekere ketoacidosis; HbA1c, hemoglobin ea glycated; HCL, lebasetere le koetsoeng loop; MDI, liente tse ngata tsa letsatsi le letsatsi, ST, phekolo e tloaelehileng; T1D, lefu la tsoekere la mofuta oa 1.
Litšupiso
- Brown S et al. Teko ea Multicenter ea sistimi ea phepelo ea insulin e se nang li-tube, 'meleng e nang le lipehelo tsa glycemic tsa bana le batho ba baholo ba nang le lefu la tsoekere la mofuta oa 1. Tlhokomelo ea Lefu la tsoekere. 2021;44(7):1630-1640.
- Sherr JL le ba bang. Tšireletseho le liphetho tsa glycemic tse nang le sistimi ea ho fana ka insulin e ikemetseng ho bana ba banyenyane haholo ba nang le lefu la tsoekere la mofuta oa 1: teko ea bongaka ea letsoho le le leng, e mengata e fapaneng. Tlhokomelo ea Lefu la tsoekere. 2022; doi: 10.2337/dc21-2359 [Inthaneteng pele ho khatiso].
© 2022 Insulet Corporation. Omnipod, SmartAdjust, le Omnipod 5 logo ke matshwao a kgwebo kapa matshwao a kgwebo a ngodisitsweng a Insulet Corporation naheng ya United States of America le dibakeng tse ding tse fapaneng. Litokelo tsohle li sirelelitsoe. Dexcom le Dexcom G6 ke matshwao a kgwebo a ngodisitsweng a Dexcom, Inc. mme a sebediswa ka tumello. Matshwao a mang kaofela ke thepa ya beng ba ona. Tšebeliso ea matšoao a mang a mang ha e fane ka tumello kapa ho fana ka maikutlo a kamano kapa kamano e 'ngoe. 1 King St, Hammersmith London W6 9HR INS-OHS-07-2022-00001 v.1
Litokomane / Lisebelisoa
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